PTC-209
目录号: A13826
BMI-1 抑制剂
PTC-209 是一种新型的高效选择性 BMI-1 抑制剂,针对 BMI-1 自我更新机制,具有约 0.5 μM 的 IC50。
| Discription | PTC-209 is a novel potent and selective BMI-1 inhibitor, targeting the BMI-1 self-renewal machinery with an IC50 of ~0.5 μM. | |||||
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| Cell Research |
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| 目录号 | A13826 |
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| 分子式 | C17H13Br2N5OS |
| 分子量 | 495.19 |
| CAS号 | 315704-66-6 |
| SMILES | CC1=C(N2C=CC=NC2=N1)C3=CSC(=N3)NC4=C(C=C(C=C4Br)OC)Br |
| 其他名称 | PTC209, PTC 209 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 92 mg/mL (185.78 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.19 mL | 100.97 mL | 201.94 mL |
| 0.5 mM | 4.04 mL | 20.19 mL | 40.39 mL |
| 1 mM | 2.02 mL | 10.1 mL | 20.19 mL |
| 5 mM | 0.4 mL | 2.02 mL | 4.04 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2