PTC124 (Ataluren)

目录号: A10758

CFTR 抑制剂

PTC124 (Ataluren)

PTC124 (Ataluren) Chemical Structure

CAS NO. 775304-57-9

PTC124也称为Ataluren,是CFTR-G542X无意义等位基因抑制剂。

库存: 现货

规格 价格 数量
10 mg
¥ 400.00
25 mg
¥ 800.00
50 mg
¥ 1,200.00
100 mg
¥ 2,000.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PTC124也称为Ataluren,是CFTR-G542X无意义等位基因抑制剂。
靶点信息
CFTR (HEK293 cells)
In vitro (25°C) DMSO 55 mg/mL (193.49 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.19 mL 175.93 mL 351.86 mL
0.5 mM 7.04 mL 35.19 mL 70.37 mL
1 mM 3.52 mL 17.59 mL 35.19 mL
5 mM 0.7 mL 3.52 mL 7.04 mL

*The above data is based on the productmolecular weight 284.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10758
作用机制 Inhibitor (抑制剂)
M. Wt 284.2
Formula C15H9FN2O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 775304-57-9
Synonyms PTC-124, PTC 124
SMILES C1=CC=C(C(=C1)C2=NC(=NO2)C3=CC(=CC=C3)C(=O)O)F

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