PTC299
            目录号: A18935
    
            VEGFA 抑制剂
    
								
							PTC299 是一种有效的、可口服的 VEGFA 抑制剂,其靶向 二氢乳酸脱氢酶 (DHODH),导致白血病(包括急性髓细胞性白血病)中的细胞生长抑制和分化,将 DHODH 调控与应激诱导的 VEGFA 和 血管生成 相联系。
        | Discription | PTC299 is a potent, orally bioavailable VEGFA inhibitor, targets dihydroorotate dehydrogenase (DHODH), resulting in cell growth inhibition and differentiation in leukemias, including acute myeloid leukemia, linking DHODH regulation and stress-induced VEGFA and angiogenesis. | |||||
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| 目录号 | A18935 | 
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| 分子式 | C25H20Cl2N2O3 | 
| 分子量 | 467.34 | 
| CAS号 | 1256565-36-2 | 
| SMILES | O=C(N([C@H]1C2=CC=C(OC)C=C2)CCC3=C1NC4=C3C=C(Cl)C=C4)OC5=CC=C(Cl)C=C5 | 
| 其他名称 | PTC-299, PTC 299 | 
| 储存条件 | Store lyophilized at -20ºC, keep desiccated.   | 
				
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2