Purvalanol A

目录号: A15517

CDK inhibitor

Purvalanol A Chemical Structure

CAS NO. 212844-53-6

Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor. IC50 values are 4, 70, 35, 850 and 75 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively.

库存: 现货

规格 价格 数量
10 mg
¥ 750.00
25 mg
¥ 1,200.00
50 mg
¥ 1,750.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor. IC50 values are 4, 70, 35, 850 and 75 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively.
靶点信息
Cdc2/CyclinB CDK2/CyclinE CDK2/CyclinA CDK4/CyclinD1
4 nM35 nM70 nM850 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.71 mL 128.57 mL 257.14 mL
0.5 mM 5.14 mL 25.71 mL 51.43 mL
1 mM 2.57 mL 12.86 mL 25.71 mL
5 mM 0.51 mL 2.57 mL 5.14 mL

*The above data is based on the productmolecular weight 388.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15517
MECHANISM OF ACTION Inhibitor
M. Wt 388.89
Formula C19H25ClN6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 212844-53-6
Synonyms NG-60
SMILES CC(C)N1C2=NC(N[C@H](C(C)C)CO)=NC(NC3=CC(Cl)=CC=C3)=C2N=C1

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