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Purvalanol B

促销

CDK 抑制剂

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产品目录号: A12352

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Purvalanol B 10mg A12352-10
¥ 1,200.00
Purvalanol B 25mg A12352-25
¥ 2,500.00
Purvalanol B 50mg A12352-50
¥ 4,500.00
Purvalanol B 100mg A12352-100
¥ 8,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Purvalanol B is a cyclin-dependent kinase inhibitor. IC50 values are 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Selective over a range of other protein kinases (IC50 > 10,000 nM).

Purvalanol B

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Chemical Information

目录号 A12352
Mechanism of action Inhibitor
分子量 432.91
化学分子式 C20H25ClN6O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 212844-54-7
Synonyms NG 95
SMILES code CC(C)[C@H](CO)NC1=NC2=C(C(=N1)NC3=CC(=C(C=C3)C(=O)O)Cl)N=CN2C(C)C
化学名称 (2R)-2-[[6-[(3-Chloro-4-carboxyphen?yl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3?-methyl-1-butanol

生物活性

Description
Purvalanol B is a cyclin-dependent kinase inhibitor. IC50 values are 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Selective over a range of other protein kinases (IC50 > 10,000 nM).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.1 mL 115.5 mL 230.99mL
0.5 mM 4.62 mL 23.1 mL 46.2 mL
1 mM 2.31 mL 11.55 mL 23.1 mL
5 mM 0.46 mL 2.31 mL 4.62 mL

*The above data is based on the productmolecular weight 432.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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