PX 12

Name: PX 12
SKU: A13831
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A13831

Trx-1 抑制剂

PX 12 抑制缺氧诱导的 HIF-1a 转录活性（IC50 为 11 nM）以及 HT29 和 MCF-7 肿瘤细胞的增殖（IC50 分别为 1.9 和 0.9 uM）。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥420.00	现货
25mg	¥875.00	现货
50mg	¥1,680.00	现货
100mg	¥2,835.00	现货
500mg	¥6,545.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

PX 12 inhibits hypoxia-induced HIF-1a transcriptional activity (IC50 11 nM) and proliferation of HT29 and MCF-7 tumor cells (IC50 1.9 and 0.9 uM, respectively).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13831
分子式	C7H12N2S2
分子量	188.31
CAS号	141400-58-0
SMILES	CCC(C)SSC1=NC=CN1
其他名称	IV-2, PX-12, PX12
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	37 mg/mL (196.48 mM)
	Water	Insoluble
	Ethanol	37 mg/mL
In vivo	2% DMSO+30% PEG 300+ddH2O	10 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	53.1 mL	265.52 mL	531.04 mL
0.5 mM	10.62 mL	53.1 mL	106.21 mL
1 mM	5.31 mL	26.55 mL	53.1 mL
5 mM	1.06 mL	5.31 mL	10.62 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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