PX-478 HCl

目录号: A14319

HIF-1alpha inhibitor

PX-478 HCl Chemical Structure

CAS NO. 685898-44-6

PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potential antineoplastic activity. PX-478 has excellent activity against established human tumor xenografts, providing tumor regressions with prolonged growth delays which correlate positively with HIF-1 levels. PX-478 is a highly water soluble molecule, with good i.v., i.p. and p.o. antitumor activity.

库存: 现货

规格 价格 数量
10 mg
¥ 1,400.00
25 mg
¥ 2,500.00
50 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 850.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potential antineoplastic activity. PX-478 has excellent activity against established human tumor xenografts, providing tumor regressions with prolonged growth delays which correlate positively with HIF-1 levels. PX-478 is a highly water soluble molecule, with good i.v., i.p. and p.o. antitumor activity.
Targets
HIF-1α
In vitro DMSO 78 mg/mL (197.9 mM)
Water 78 mg/mL (197.9 mM)
Ethanol 78 mg/mL (197.9 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.37 mL 126.86 mL 253.73 mL
0.5 mM 5.07 mL 25.37 mL 50.75 mL
1 mM 2.54 mL 12.69 mL 25.37 mL
5 mM 0.51 mL 2.54 mL 5.07 mL

*The above data is based on the productmolecular weight 394.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14319
MECHANISM OF ACTION Inhibitor
M. Wt 394.12
Formula C13H20Cl4N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 685898-44-6
Synonyms 0
SMILES C1=CC(=CC=C1C[C@@H](C(=O)O)N)[N+](CCCl)(CCCl)[O-].Cl.Cl

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 PX-478 HCl | PX-478 HCl 供应商 | 订购 PX-478 HCl | PX-478 HCl 价格 | PX-478 HCl 生产商 | 订单 PX-478 HCl | PX-478 HCl 代理商 | 购买 685898-44-6| 685898-44-6 供应商 | 订购 685898-44-6 | 685898-44-6 价格 | 685898-44-6 生产商 | 订单 685898-44-6 | 685898-44-6 代理商|buy PX-478 HCl | PX-478 HCl Supplier | purchase PX-478 HCl | PX-478 HCl cost | PX-478 HCl manufacturer | order PX-478 HCl | PX-478 HCl distributor | buy 685898-44-6| 685898-44-6 Supplier | purchase 685898-44-6 | 685898-44-6 cost | 685898-44-6 manufacturer | order 685898-44-6 | 685898-44-6 distributor
Rewards