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PX-866 (Sonolisib)是磷酸肌醇3激酶(PI3K)的α，γ和δ亚型的小分子渥曼青霉素类似物抑制剂，具有潜在的抗肿瘤活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.04 mL | 95.2 mL | 190.4 mL |
| 0.5 mM | 3.81 mL | 19.04 mL | 38.08 mL |
| 1 mM | 1.9 mL | 9.52 mL | 19.04 mL |
| 5 mM | 0.38 mL | 1.9 mL | 3.81 mL |
*The above data is based on the productmolecular weight 525.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11261 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 525.2 |
| Formula | C29H35NO8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 502632-66-8 |
| Synonyms | PX866 |
| SMILES | O=C(/C1=C\N(CC=C)CC=C)O[C@H](COC)[C@@]2(C)C1=C(O)C(C3=C2[C@H](OC(C)=O)C[C@@]4(C)[C@@]3([H])CCC4=O)=O |
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