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PXS-5153A is a novel mechanism based, fast-acting, dual LOXL2/LOXL3 inhibitor, which was used to interrogate the role of these enzymes in models of collagen crosslinking and fibrosis.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.03 mL | 105.17 mL | 210.34 mL |
| 0.5 mM | 4.21 mL | 21.03 mL | 42.07 mL |
| 1 mM | 2.1 mL | 10.52 mL | 21.03 mL |
| 5 mM | 0.42 mL | 2.1 mL | 4.21 mL |
*The above data is based on the productmolecular weight 475.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18757 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 475.41 |
| Formula | C20H25Cl2FN4O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2125956-82-1 |
| Synonyms | PXS-5153A; PXS 5153A; PXS5153A; PXS-5153; PXS 5153; PXS5153; |
| SMILES | CC(N1C/C(F)=C/CN)=C(C2=CC=CC(S(N(C)C)(=O)=O)=C2)C3=C1C=CC=N3.Cl.Cl |
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