PYR-41
目录号: A13254
Ubiquitin E1 抑制剂
PYR-41 是一种细胞渗透性、不可逆的泛素激活酶（E1）抑制剂（IC50 < 10 μM）。
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生物活性
| Discription | PYR-41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM). | |||||
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产品信息
| 目录号 | A13254 |
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| 分子式 | C17H13N3O7 |
| 分子量 | 371.3 |
| CAS号 | 418805-02-4 |
| SMILES | CCOC(=O)C1=CC=C(C=C1)N2C(=O)/C(=C\C3=CC=C(O3)[N+](=O)[O-])/C(=O)N2 |
| 其他名称 | PYR 41, PYR41 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 72 mg/mL (193.9 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 1 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.93 mL | 134.66 mL | 269.32 mL |
| 0.5 mM | 5.39 mL | 26.93 mL | 53.86 mL |
| 1 mM | 2.69 mL | 13.47 mL | 26.93 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.39 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 418805-02-4 | 418805-02-4 供应商 | 418805-02-4 花费 | 418805-02-4 生产商 | 订购 418805-02-4 | 418805-02-4 代理商