Pyr10

Name: Pyr10
SKU: A20786
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A20786

TRPC3 抑制剂

1 篇发表文献

Pyr10 是一种新型的 TRPC3-选择性抑制剂，其在卡巴胆碱刺激的 YFP-TRPC3 转染 HEK293 细胞中对 ROCE 的 Ca2+ 流入抑制的 IC50 为 0.72 uM，在刺激后用 thapsigargin 耗尽的原生 RBL-2H3 细胞中对 SOCE 的 IC50 为 13.08 uM。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥315.00	现货
25mg	¥735.00	现货
50mg	¥1,400.00	现货
100mg	¥2,030.00	现货
*10mM 1mL in DMSO**	¥210.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Pyr10发表的1篇文献

Keisuke Obara, .et al. , Biol Pharm Bull, 2025, 48(6):932-940 PMID: 40582844

生物活性

Discription

Pyr10is a novel TRPC3-selective inhibitor, IC50 of Ca2+ influx inhibition by Pyr10 in carbachol-stimulated YFP-TRPC3-transfected HEK293 cells for ROCE and thapsigargin-depleted native RBL-2H3 cells for SOCE is 0.72 uM and 13.08 uM.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20786
分子式	C18H13F6N3O2S
分子量	449.37
CAS号	1315323-00-2
SMILES	O=S(C1=CC=C(C)C=C1)(NC2=CC=C(N3N=C(C(F)(F)F)C=C3C(F)(F)F)C=C2)=O
其他名称	Pyr-10; Pyr 10
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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