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Pyr6 is a selective inhibitor of TRPC3 with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.91 mL | 119.54 mL | 239.08 mL |
| 0.5 mM | 4.78 mL | 23.91 mL | 47.82 mL |
| 1 mM | 2.39 mL | 11.95 mL | 23.91 mL |
| 5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
*The above data is based on the productmolecular weight 418.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21927 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 418.27 |
| Formula | C17H9F7N4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 245747-08-4 |
| Synonyms | Pyr 6, Pyr-6 |
| SMILES | O=C(C1=C(F)C=NC=C1)NC2=CC=C(N3N=C(C(F)(F)F)C=C3C(F)(F)F)C=C2 |
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