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Pyrazofurin

Pyrazofurin

Name: Pyrazofurin
SKU: A18601

目录号: A18601

OPRTase inhibitor

Pyrazofurin Chemical Structure

CAS NO. 30868-30-5

Pyrazofurin, a pyrimidine nucleoside analogue with antineoplastic activity, inhibits cell proliferation and DNA synthesis in cells by inhibiting uridine 5'-phosphate (UMP) synthase[1]. Pyrazofurin is an active, sensitive orotate-phosphoribosyltransferase inhibitor with IC50s between 0.06-0.37 ?M in the three squamous cell carcinoma (SCC) cell lines Hep-2, HNSCC-14B and HNSCC-14C.

库存：现货

规格	价格	数量
5 mg	￥ 3,500.00
10 mg	￥ 6,500.00
50 mg	￥ 20,000.00

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制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	38.58 mL	192.89 mL	385.77 mL
0.5 mM	7.72 mL	38.58 mL	77.15 mL
1 mM	3.86 mL	19.29 mL	38.58 mL
5 mM	0.77 mL	3.86 mL	7.72 mL

*The above data is based on the productmolecular weight 259.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18601
作用机制	Inhibitor (抑制剂)
M. Wt	259.22
Formula	C9H13N3O6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	30868-30-5
SMILES	O=C(N)C1=NNC([C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)=C1O