Pyrotinib dimaleate

Name: Pyrotinib dimaleate
SKU: A21756
Price: 1050 CNY
Rating: 5 (288 reviews)

目录号: A21756

EGFR/HER2 dual 抑制剂

Pyrotinib dimaleate (SHR-1258 dimaleate) 是一种强效且选择性的 EGFR/HER2 双重抑制剂，其 IC50 分别为 13 和 38 nM。

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Grouped product items
规格	价格	库存
1mg	¥1,050.00	现货
5mg	¥3,325.00	现货
10mg	¥4,445.00	现货
25mg	¥6,930.00	现货
50mg	¥9,555.00	现货
100mg	¥12,915.00	现货
*10mM 1mL in DMSO**	¥4,515.00	现货
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Data Sheet

SDS

Other Forms of Pyrotinib dimaleate

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生物活性

Discription

Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50 s of 13 and 38 nM, respectively.

Targets

Target	Value

产品信息

目录号	A21756
分子式	C40H39ClN6O11
分子量	815.22
CAS号	1397922-61-0
SMILES	O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/[C@@H]5N(C)CCC5.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O
其他名称	SHR-1258 dimaleate, SHR1258, SHR 1258
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Insoluble
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.27 mL	61.33 mL	122.67 mL
0.5 mM	2.45 mL	12.27 mL	24.53 mL
1 mM	1.23 mL	6.13 mL	12.27 mL
5 mM	0.25 mL	1.23 mL	2.45 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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