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Q-VD-OPh hydrate

促销

Caspase 抑制剂

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产品目录号: A14915

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Q-VD-OPh hydrate 5mg A14915-5
¥ 900.00
Q-VD-OPh hydrate 10mg A14915-10
¥ 1,500.00
Q-VD-OPh hydrate 25mg A14915-25
¥ 2,400.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM).

Q-VD-OPh hydrate

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Chemical Information

目录号 A14915
Mechanism of action Inhibitor
分子量 513.49
化学分子式 C26H25F2N3O6
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1135695-98-5
Synonyms N/A
SMILES code CC(C)C(C(=O)NC(CC(=O)O)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C2=NC3=CC=CC=C3C=C2
化学名称 (3S)-5-(2,6-Difluorophenoxy)-3-[[(2S)-3-methyl-1-oxo-2-[(2-quinolinylcarbonyl)amino]butyl]amino]-4-oxo-pentanoic acid

生物活性

Description
Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM).
Targets
Caspase-1 Caspase-3 Caspase-8 Caspase-9
25 nM-400 nM25 nM-400 nM25 nM-400 nM25 nM-400 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.47 mL 97.37 mL 194.75mL
0.5 mM 3.89 mL 19.47 mL 38.95 mL
1 mM 1.95 mL 9.74 mL 19.47 mL
5 mM 0.39 mL 1.95 mL 3.89 mL

*The above data is based on the productmolecular weight 513.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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