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mTORC1/2 抑制剂

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产品目录号: A11537


产品名 目录号 价格 数量
QL-IX-55 5mg A11537-5
¥ 3,500.00
QL-IX-55 10mg A11537-10
¥ 6,000.00
QL-IX-55 50mg A11537-50
¥ 22,000.00



QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively.





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Chemical Information

目录号 A11537
Mechanism of action Inhibitor
分子量 450.39
化学分子式 C24H14F4N4O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1223002-54-7
Synonyms N/A
SMILES code C1=CC2=NC=C3C=CC(=O)N(C3=C2C=C1C4=CN=C(C=C4)N)C5=CC(=C(C=C5)F)C(F)(F)F
化学名称 9-(6-aminopyridin-3-yl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2-one


QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.2 mL 111.01 mL 222.03mL
0.5 mM 4.44 mL 22.2 mL 44.41 mL
1 mM 2.22 mL 11.1 mL 22.2 mL
5 mM 0.44 mL 2.22 mL 4.44 mL

*The above data is based on the productmolecular weight 450.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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