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QNZ (EVP4593)


NF-??B 抑制剂

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产品目录号: A12748


产品名 目录号 价格 数量
QNZ 5mg A12748-5
¥ 500.00
QNZ 10mg A12748-10
¥ 800.00
QNZ 25mg A12748-25
¥ 1,500.00
QNZ 50mg A12748-50
¥ 2,500.00



QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling.

QNZ (EVP4593)




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Chemical Information

目录号 A12748
Mechanism of action Inhibitor
分子量 356.4
化学分子式 C22H20N4O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 545380-34-5
Synonyms CAY10470, CAY 10470, CAY-10470
化学名称 N4-?[2-?(4-?phenoxyphenyl)ethyl]-?4,?6-?quinazolinediamine


QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling.
TNF-α (Jurkat T cells) NF-κB (Jurkat T cells)
7 nM11 nM


Solubility (25°C) * In vitro DMSO 5 mg/mL (14.02 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.06 mL 140.29 mL 280.58mL
0.5 mM 5.61 mL 28.06 mL 56.12 mL
1 mM 2.81 mL 14.03 mL 28.06 mL
5 mM 0.56 mL 2.81 mL 5.61 mL

*The above data is based on the productmolecular weight 356.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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