Quilizumab is a humanized IgG1?? monoclonal antibody specifically designed to target immunoglobulin epsilon (IGHE, commonly referred to as IgE). This antibody binds to the M1-prime fragment of the membrane-expressed form of IGHE/IgE. The interaction promotes IGHE/IgE class switching and facilitates the depletion of memory B cells. Given its unique mechanism of action, Quilizumab holds significant potential for advancing research in asthma and other IgE-mediated conditions.
Quilizumab is a humanized IgG1?? monoclonal antibody specifically designed to target immunoglobulin epsilon (IGHE, commonly referred to as IgE). This antibody binds to the M1-prime fragment of the membrane-expressed form of IGHE/IgE. The interaction promotes IGHE/IgE class switching and facilitates the depletion of memory B cells. Given its unique mechanism of action, Quilizumab holds significant potential for advancing research in asthma and other IgE-mediated conditions.
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