Quinolinic acid
目录号: A20575
NMDA receptor 激动剂
奎尼林酸是一种内源性 N-甲基-D-天冬氨酸(NMDA)受体激动剂,通过色氨酸代谢途径从L-色氨酸合成,因此具有介导 N-甲基-D-天冬氨酸 神经元损伤和功能障碍的潜力。
| Discription | Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction. | ||
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| 目录号 | A20575 |
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| 分子式 | C7H5NO4 |
| 分子量 | 167.12 |
| CAS号 | 89-00-9 |
| SMILES | O=C(C1=NC=CC=C1C(O)=O)O |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 22 mg/mL (131.64 mM) | |
| Water | 3 mg/mL (17.95 mM) | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 59.84 mL | 299.19 mL | 598.37 mL |
| 0.5 mM | 11.97 mL | 59.84 mL | 119.67 mL |
| 1 mM | 5.98 mL | 29.92 mL | 59.84 mL |
| 5 mM | 1.2 mL | 5.98 mL | 11.97 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2