R-10015
目录号: A18806
LIMK 抑制剂
R-10015 是一种针对 HIV 感染的广谱抗病毒化合物,它作为 LIM 域激酶 (LIMK) 的强效和选择性抑制剂,并与 ATP 结合口袋结合,对人类 LIMK1 的 IC50 为 38 nM。
Discription | R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1. | ||
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目录号 | A18806 |
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分子式 | C20H19ClN6O2 |
分子量 | 410.86 |
CAS号 | 2097938-51-5 |
SMILES | O=C(C1=CC=C2NC(C3CCN(C4=C5C(NC=C5Cl)=NC=N4)CC3)=NC2=C1)OC |
其他名称 | R10015, R 10015 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 76 mg/mL (184.98 mM) | |
Water | <1 mg/mL | ||
Ethanol | 9 mg/mL (21.9 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.34 mL | 121.7 mL | 243.39 mL |
0.5 mM | 4.87 mL | 24.34 mL | 48.68 mL |
1 mM | 2.43 mL | 12.17 mL | 24.34 mL |
5 mM | 0.49 mL | 2.43 mL | 4.87 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2