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R-10015

目录号: A18806
LIMK 抑制剂
R-10015 是一种针对 HIV 感染的广谱抗病毒化合物,它作为 LIM 域激酶 (LIMK) 的强效和选择性抑制剂,并与 ATP 结合口袋结合,对人类 LIMK1 的 IC50 为 38 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥420.00
现货
5mg
¥1,155.00
现货
10mg
¥1,855.00
现货
25mg
¥3,080.00
现货
50mg
¥4,095.00
现货
100mg
¥5,775.00
现货
200mg
¥7,875.00
现货
10mM * 1mL in DMSO
¥1,295.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1.
Targets
Target Value
产品信息
目录号 A18806
分子式 C20H19ClN6O2
分子量 410.86
CAS号 2097938-51-5
SMILES O=C(C1=CC=C2NC(C3CCN(C4=C5C(NC=C5Cl)=NC=N4)CC3)=NC2=C1)OC
其他名称 R10015, R 10015
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 76 mg/mL (184.98 mM)
Water <1 mg/mL
Ethanol 9 mg/mL (21.9 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.34 mL 121.7 mL 243.39 mL
0.5 mM 4.87 mL 24.34 mL 48.68 mL
1 mM 2.43 mL 12.17 mL 24.34 mL
5 mM 0.49 mL 2.43 mL 4.87 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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