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(R)-BAY1238097

目录号: A21593
BET binding to histones 抑制剂
(R)-BAY1238097 是 BAY1238097 的 R-异构体,具有较低的活性。BAY1238097 是一种强效且选择性的 BET 与组蛋白结合的抑制剂,并且在不同的 AML(急性髓性白血病)和 MM(多发性骨髓瘤)模型中具有强大的抗增殖活性,这是通过下调 c-Myc 水平及其下游转录组实现的。
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规格 价格 库存 数量
5mg
¥945.00
现货
10mg
¥1,610.00
现货
25mg
¥3,920.00
现货
50mg
¥6,195.00
现货
100mg
¥10,255.00
现货
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生物活性
Discription (R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome.
产品信息
目录号 A21593
分子式 C25H33N5O3
分子量 451.56
CAS号 1564269-85-7
SMILES O=C(N1N=C(C2=CC=C(N3CCN(C)CC3)C=C2)C4=CC(OC)=C(OC)C=C4C[C@H]1C)NC
其他名称 BAY 1238097, BAY1238097
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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