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(R)-GNE-140

(R)-GNE-140

Name: (R)-GNE-140
SKU: A21863

目录号: A21863

LDHA inhibitor

(R)-GNE-140 Chemical Structure

CAS NO. 2003234-63-5

(R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor, with IC50s of 3 nM and 5 nM for LDHA and LDHB, respectively; (R)-GNE-140 is 18-fold more potent than S enantiomer.

库存：现货

规格	价格	数量
1 mg	￥ 1,080.00
5 mg	￥ 3,240.00
10 mg	￥ 5,520.00
50 mg	￥ 16,560.00

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生物活性

(R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor, with IC50s of 3 nM and 5 nM for LDHA and LDHB, respectively; (R)-GNE-140 is 18-fold more potent than S enantiomer.

溶解度 *

In vitro	DMSO	88 mg/mL (176.33 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.04 mL	100.19 mL	200.38 mL
0.5 mM	4.01 mL	20.04 mL	40.08 mL
1 mM	2 mL	10.02 mL	20.04 mL
5 mM	0.4 mL	2 mL	4.01 mL

*The above data is based on the productmolecular weight 499.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21863
作用机制	Inhibitor (抑制剂)
M. Wt	499.04
Formula	C25H23ClN2O3S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2003234-63-5
Synonyms	GNE140, GNE 140
SMILES	O=C1N[C@@](C2=CSC=C2)(C3=CC=C(N4CCOCC4)C=C3)CC(O)=C1SC5=CC=CC=C5Cl