R428

目录号: A13741

Axl Inhibitor

R428 Chemical Structure

CAS NO. 1037624-75-1

R428 is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer.

库存: 现货

规格 价格 数量
2 mg
¥ 500.00
5 mg
¥ 900.00
10 mg
¥ 1,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

R428 is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer.
靶点信息
Axl
14 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.74 mL 98.69 mL 197.38 mL
0.5 mM 3.95 mL 19.74 mL 39.48 mL
1 mM 1.97 mL 9.87 mL 19.74 mL
5 mM 0.39 mL 1.97 mL 3.95 mL

*The above data is based on the productmolecular weight 506.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13741
MECHANISM OF ACTION Inhibitor
M. Wt 506.64
Formula C30H34N8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1037624-75-1
Synonyms BGB324, BGB 324, BGB-324, R-428
SMILES C1CCN(C1)[C@H]2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76

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