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R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.65 mL | 93.27 mL | 186.54 mL |
| 0.5 mM | 3.73 mL | 18.65 mL | 37.31 mL |
| 1 mM | 1.87 mL | 9.33 mL | 18.65 mL |
| 5 mM | 0.37 mL | 1.87 mL | 3.73 mL |
*The above data is based on the productmolecular weight 536.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19374 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 536.09 |
| Formula | C26H30ClN9S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1037798-41-6 |
| Synonyms | R 916562, R-916562 |
| SMILES | NC1=NC(NC(C=C2)=CC=C2N3CCN([C@H]4[C@@H]5CC[C@@H](C5)C4)CC3)=NN1C6=NC(Cl)=NC7=C6SC=C7C |
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