(Rac)-JBJ-04-125-02
目录号: A22141
EGFR 抑制剂
(Rac)-JBJ-04-125-02 是 JBJ-04-125-02 的外消旋体。JBJ-04-125-02 是一种强效的、选择性突变体、变构且可口服的 EGFR 抑制剂,对 EGFRL858R/T790M 的 IC50 为 0.26 nM。
Discription | (Rac)-JBJ-04-125-02 is the racemate of JBJ-04-125-02. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M. | |||||
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Cell Research |
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目录号 | A22141 |
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分子式 | C29H26FN5O3S |
分子量 | 543.61 |
CAS号 | 2140807-05-0 |
SMILES | O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N(CC3=C4C=C(C5=CC=C(N6CCNCC6)C=C5)C=C3)C4=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2