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(Rac)-JBJ-04-125-02 is the racemate of JBJ-04-125-02. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.4 mL | 91.98 mL | 183.96 mL |
| 0.5 mM | 3.68 mL | 18.4 mL | 36.79 mL |
| 1 mM | 1.84 mL | 9.2 mL | 18.4 mL |
| 5 mM | 0.37 mL | 1.84 mL | 3.68 mL |
*The above data is based on the productmolecular weight 543.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22141 |
|---|---|
| M. Wt | 543.61 |
| Formula | C29H26FN5O3S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 2140807-05-0 |
| SMILES | O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N(CC3=C4C=C(C5=CC=C(N6CCNCC6)C=C5)C=C3)C4=O |
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