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Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.8 mL | 143.99 mL | 287.99 mL |
| 0.5 mM | 5.76 mL | 28.8 mL | 57.6 mL |
| 1 mM | 2.88 mL | 14.4 mL | 28.8 mL |
| 5 mM | 0.58 mL | 2.88 mL | 5.76 mL |
*The above data is based on the productmolecular weight 347.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19204 |
|---|---|
| M. Wt | 347.24 |
| Formula | C15H20Cl2N2O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 84225-95-6 |
| SMILES | O=C(NC[C@H]1N(CC)CCC1)C2=C(OC)C(Cl)=CC(Cl)=C2O |
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