Radiprodil
目录号: A21193
NMDA NR2B 拮抗剂
Radiprodil (RGH-896) 是一种口服活性且选择性的 NMDA NR2B 拮抗剂。它是治疗神经病性疼痛以及可能的其他慢性疼痛状况的潜在治疗药物。
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生物活性
| Discription | Radiprodil (RGH-896) is an orally active and selective NMDA NR2B antagonist. A potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions. |
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产品信息
| 目录号 | A21193 |
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| 分子式 | C21H20FN3O4 |
| 分子量 | 397.4 |
| CAS号 | 496054-87-6 |
| SMILES | O=C(NC1=CC=C2NC(OC2=C1)=O)C(N3CCC(CC4=CC=C(F)C=C4)CC3)=O |
| 其他名称 | RGH-896, RGH896, RGH 896 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 75 mg/mL (188.72 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.16 mL | 125.82 mL | 251.64 mL |
| 0.5 mM | 5.03 mL | 25.16 mL | 50.33 mL |
| 1 mM | 2.52 mL | 12.58 mL | 25.16 mL |
| 5 mM | 0.5 mL | 2.52 mL | 5.03 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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