Radotinib (IY-5511)
目录号: A13029
Bcr-Abl tyrosine 抑制剂?€?
Radotinib 是一种新型且选择性的 Bcl-Abl 酪氨酸激酶抑制剂。
| Discription | Radotinib is a novel and selective Bcl-Abl tyrosine kinase inhibitor | ||
|---|---|---|---|
| Targets |
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| 目录号 | A13029 |
|---|---|
| 分子式 | C27H21F3N8O |
| 分子量 | 530.5 |
| CAS号 | 926037-48-1 |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=NC=CN=C5 |
| 其他名称 | IY-5511 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 94 mg/mL (177.19 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.85 mL | 94.25 mL | 188.5 mL |
| 0.5 mM | 3.77 mL | 18.85 mL | 37.7 mL |
| 1 mM | 1.89 mL | 9.43 mL | 18.85 mL |
| 5 mM | 0.38 mL | 1.89 mL | 3.77 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2