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RAF mutant-IN-1

RAF mutant-IN-1

Name: RAF mutant-IN-1
SKU: A19011

目录号: A19011

Raf nhibitor

RAF mutant-IN-1 Chemical Structure

CAS NO. 2340020-82-6

RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF340D/Y341D, B-RAFV600E and B-RAFWT, respectively.

库存：现货

规格	价格	数量
1 mg	￥ 3,200.00
5 mg	￥ 9,600.00
10 mg	￥ 16,000.00

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生物活性

RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF340D/Y341D, B-RAFV600E and B-RAFWT, respectively.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.61 mL	88.05 mL	176.1 mL
0.5 mM	3.52 mL	17.61 mL	35.22 mL
1 mM	1.76 mL	8.81 mL	17.61 mL
5 mM	0.35 mL	1.76 mL	3.52 mL

*The above data is based on the productmolecular weight 567.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19011
作用机制	Inhibitor (抑制剂)
M. Wt	567.85
Formula	C23H18Cl3FN6O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2340020-82-6
SMILES	O=C(C1=CSC2=C(N)N=CN=C21)NC3=C(C)C=CC4=C3C=CN=C4NC5=CC=C(O)C(Cl)=C5F.[H]Cl.[H]Cl