RAF265 (CHIR-265)

Name: RAF265 (CHIR-265)
SKU: A10773
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A10773

RAF/VEGFR 抑制剂

RAF265（CHIR-265）是一种口服、高度选择性的RAF和VEGFR激酶抑制剂，用于控制或正常化VEGFR-2，并同时抑制B-raf和c-Raf突变以预防癌症。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥350.00	现货
5mg	¥560.00	现货
10mg	¥1,015.00	现货
25mg	¥1,925.00	现货
50mg	¥3,150.00	现货
100mg	¥4,655.00	现货
*10mM 1mL in DMSO**	¥665.00	现货
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Data Sheet

SDS

Other Forms of RAF265 (CHIR-265)

Raf265 derivative

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生物活性

Discription

RAF265 (CHIR-265) is an oral, highly selective RAF and VEGFR kinase inhibitor, which is to control or normalize VEGFR-2 along with the inhibition of B-raf and c-Raf mutation to prevent cancers.

Targets

Target	Value

产品信息

目录号	A10773
分子式	C24H16F6N6O
分子量	518.4
CAS号	927880-90-8
SMILES	CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	85 mg/mL (163.96 mM)
	Water	Insoluble
	Ethanol	28 mg/mL (54.01 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.29 mL	96.45 mL	192.9 mL
0.5 mM	3.86 mL	19.29 mL	38.58 mL
1 mM	1.93 mL	9.65 mL	19.29 mL
5 mM	0.39 mL	1.93 mL	3.86 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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