RAF265 (CHIR-265)

目录号: A10773

RAF/VEGFR Inhibitor

RAF265 (CHIR-265) Chemical Structure

CAS NO. 927880-90-8

RAF265 (CHIR-265) is an oral, highly selective RAF and VEGFR kinase inhibitor, which is to control or normalize VEGFR-2 along with the inhibition of B-raf and c-Raf mutation to prevent cancers.

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
25 mg
¥ 3,800.00
50 mg
¥ 6,500.00
10mM * 1mL in DMSO
¥ 1,830.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

RAF265 (CHIR-265) is an oral, highly selective RAF and VEGFR kinase inhibitor, which is to control or normalize VEGFR-2 along with the inhibition of B-raf and c-Raf mutation to prevent cancers.
Targets
VEGFR2 (Cell-free assay) B-Raf (Cell-free assay)
30 nM(EC50)3 nM-60 nM
In vitro (25°C) DMSO 100 mg/mL (192.89 mM)
Water <1 mg/mL (<1 mM)
Ethanol 33 mg/mL (63.65 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.29 mL 96.45 mL 192.9 mL
0.5 mM 3.86 mL 19.29 mL 38.58 mL
1 mM 1.93 mL 9.65 mL 19.29 mL
5 mM 0.39 mL 1.93 mL 3.86 mL

*The above data is based on the productmolecular weight 518.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10773
MECHANISM OF ACTION Inhibitor
M. Wt 518.4
Formula C24H16F6N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 927880-90-8
Synonyms N/A
SMILES CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
您还可能对下列产品感兴趣
Keywords:购买 RAF265 (CHIR-265) | RAF265 (CHIR-265) 供应商 | 订购 RAF265 (CHIR-265) | RAF265 (CHIR-265) 价格 | RAF265 (CHIR-265) 生产商 | 订单 RAF265 (CHIR-265) | RAF265 (CHIR-265) 代理商 | 购买 927880-90-8| 927880-90-8 供应商 | 订购 927880-90-8 | 927880-90-8 价格 | 927880-90-8 生产商 | 订单 927880-90-8 | 927880-90-8 代理商|buy RAF265 (CHIR-265) | RAF265 (CHIR-265) Supplier | purchase RAF265 (CHIR-265) | RAF265 (CHIR-265) cost | RAF265 (CHIR-265) manufacturer | order RAF265 (CHIR-265) | RAF265 (CHIR-265) distributor | buy 927880-90-8| 927880-90-8 Supplier | purchase 927880-90-8 | 927880-90-8 cost | 927880-90-8 manufacturer | order 927880-90-8 | 927880-90-8 distributor
Rewards