Ralimetinib

Name: Ralimetinib
SKU: A21942
Price: 1400 CNY
Rating: 5 (288 reviews)

目录号: A21942

p38 MAPK α/β 抑制剂

Ralimetinib（LY2228820）是一种强效且选择性的，与ATP竞争的p38 MAPK α/β抑制剂，其IC50分别为5.3和3.2 nM。

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Grouped product items
规格	价格	库存
1mg	¥1,400.00	现货
5mg	¥3,500.00	现货
10mg	¥5,600.00	现货
25mg	¥10,605.00	现货
50mg	¥13,825.00	现货
100mg	¥17,465.00	现货
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Data Sheet

SDS

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生物活性

Discription

Ralimetinib (LY2228820) is a potent and selective, ATP-competitive inhibitor of p38 MAPK α/β, with IC50s of 5.3 and 3.2 nM, respectively.

Targets

Target	Value

产品信息

目录号	A21942
分子式	C24H29FN6
分子量	420.53
CAS号	862505-00-8
SMILES	NC1=NC2=CC=C(C3=C(C4=CC=C(F)C=C4)N=C(C(C)(C)C)N3)N=C2N1CC(C)(C)C
其他名称	LY2228820, LY 2228820, LY-2228820
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 30 mg/mL (48.9 mM)
	Water	Warmed: 85 mg/mL (138.72 mM)
	Ethanol	3 mg/mL (4.89 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.78 mL	118.9 mL	237.8 mL
0.5 mM	4.76 mL	23.78 mL	47.56 mL
1 mM	2.38 mL	11.89 mL	23.78 mL
5 mM	0.48 mL	2.38 mL	4.76 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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