Ramelteon (TAK-375)

Name: Ramelteon (TAK-375)
SKU: A10777
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A10777

MT1/MT2-Receptor 激动剂

Ramelteon 是一种褪黑素受体激动剂，对褪黑素 MT1（IC50 = 28.5 ± 8.55 pM）和 MT2（20.1 ± 9.25 pM）受体具有高亲和力，并且相对于 MT3 受体具有选择性。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥350.00	现货
10mg	¥490.00	现货
25mg	¥805.00	现货
50mg	¥1,365.00	现货
100mg	¥2,345.00	现货
500mg	¥3,710.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

Ramelteon is a melatonin receptor agonist with both high affinity for melatonin MT1 (IC50 =28.5 ?? 8.55 pM)and MT2 (20.1 ?? 9.25 pM)receptors and selectivity over the MT3 receptor.

Targets

Target	Value

产品信息

目录号	A10777
分子式	C16H21NO2
分子量	259.3
CAS号	196597-26-9
SMILES	CCC(=O)NCC[C@@H]1CCC2=C1C3=C(C=C2)OCC3
其他名称	Rozerem, TAK-375, TAK375
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	47 mg/mL (181.22 mM)
	Water	Insoluble
	Ethanol	47 mg/mL (181.22 mM)
In vivo	0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	38.57 mL	192.83 mL	385.65 mL
0.5 mM	7.71 mL	38.57 mL	77.13 mL
1 mM	3.86 mL	19.28 mL	38.57 mL
5 mM	0.77 mL	3.86 mL	7.71 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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