Rapamycin (Sirolimus)

Name: Rapamycin (Sirolimus)
SKU: A10782
Price: 175 CNY
Rating: 5 (18 reviews)

目录号: A10782

mTOR 抑制剂s

18 篇发表文献

Rapamycin（Sirolimus）通过抑制T细胞和B细胞对白细胞介素-2（IL-2）的反应，阻止它们的激活。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥175.00	现货
25mg	¥245.00	现货
50mg	¥280.00	现货
100mg	¥385.00	现货
200mg	¥700.00	现货
500mg	¥1,330.00	现货
1g	¥2,030.00	现货
2g	¥3,920.00	现货
5g	¥7,350.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Rapamycin (Sirolimus)发表的18篇文献

Saudatu Faruk, .et al. , J Trace Elem Med Biol, 2025, Sep 6:92:127740 PMID: 40945136

Saudatu Faruk, .et al. , Biol Trace Elem Res, 2025, May 8 PMID: 40338453

Saudat Faruk, .et al. , Iron, 2025, March

Yudong Li, .et al. , J Polym Sci, 2024, 62:2215-2230

Ross van de Weterin, .et al. , Glia, 2024, Jun 20 PMID: 38899723

Yuanqin Zhang, .et al. , Cancers (Basel), 2023, Dec 2;15(23):5691 PMID: 38067394

Amnon Wittenstein, .et al. , PLoS Biol, 2023, Nov 9;21(11):e3002355 PMID: 37943958

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Hideki Kawasaki, .et al. , J Insect Physiol, 2023, Mar;145:104476 PMID: 36623750

R Mahalakshmi, .et al. , Mol Biol Rep, 2022, Jan;49(1):463-476 PMID: 34739690

Yusuke Murase, .et al. , Oncol Rep, 2022, Apr;47(4):61 PMID: 35088890

Zhichao Wu, .et al. , Cells, 2021, Oct 27;10(11):2912 PMID: 34831135

Matthew A Schaller, .et al. , JCI Insight, 2021, Sep 22;6(18):e148003 PMID: 34357881

Matthew A. Schaller, .et al. , bioRxiv, 2021, January 21

Ashley VanCleave, .et al. , Oncotarget, 2020, Jul 7; 11(27): 2597-2610 PMID: 32676162

Y Huang, .et al. , Experimental and Therapeutic Medicine, 2020, 20(2), 736-747 PMID: 32742319

Takuya Hirao, .et al. , Cancer Sci, 2018, Jan; 109(1): 121-131 PMID: 29121435

Ya-Hui Chen, .et al. , J Diabetes Res, 2016, 2016: 1828071 PMID: 28004006

生物活性

Discription

Rapamycin (Sirolimus) prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10782
分子式	C51H79NO13
分子量	914.2
CAS号	53123-88-9
SMILES	C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC
其他名称	Rapamune
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	18 mg/mL (19.68 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.94 mL	54.69 mL	109.39 mL
0.5 mM	2.19 mL	10.94 mL	21.88 mL
1 mM	1.09 mL	5.47 mL	10.94 mL
5 mM	0.22 mL	1.09 mL	2.19 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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