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Rapamycin (Sirolimus)


mTOR 抑制剂s

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产品目录号: A10782


产品名 目录号 价格 数量
Rapamycin 5mg A10782-5
¥ 400.00
Rapamycin 25mg A10782-25
¥ 1,200.00
Rapamycin 50mg A10782-50
¥ 2,000.00
Rapamycin 100mg A10782-100
¥ 3,500.00
Rapamycin (Sirolimus) 10mM * 1mL in DMSO A10782-10mM-D
¥ 1,320.00



Rapamycin (Sirolimus) prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2).

Rapamycin (Sirolimus)




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Rapamycin (Sirolimus) 发表的文献 (2)
  • Takuya Hirao, .et al. Altered intracellular signaling by imatinib increases the anti坼cancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia cells, Cancer Sci, 2018, Jan; 109(1): 121每131 PMID: 29121435
  • Ya-Hui Chen, .et al. The Different Effects of Atorvastatin and Pravastatin on Cell Death and PARP Activity in Pancreatic NIT-1 Cells, J Diabetes Res, 2016, 2016: 1828071 PMID: 28004006

Chemical Information

目录号 A10782
Mechanism of action Inhibitor
分子量 914.2
化学分子式 C51H79NO13
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 53123-88-9
Synonyms Rapamune
SMILES code C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC
化学名称 N/A


Rapamycin (Sirolimus) prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2).
mTOR (HEK293 cells)
~0.1 nM


Solubility (25°C) * In vitro DMSO 20 mg/mL (21.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC/0.25% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.94 mL 54.69 mL 109.39mL
0.5 mM 2.19 mL 10.94 mL 21.88 mL
1 mM 1.09 mL 5.47 mL 10.94 mL
5 mM 0.22 mL 1.09 mL 2.19 mL

*The above data is based on the productmolecular weight 914.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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