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Reboxetine mesylate

目录号: A11919
Reboxetine 是一种抗抑郁药物,它选择性地抑制去甲肾上腺素的摄取(IC50 分别为 8.2 和 1,070 nM,针对去甲肾上腺素和5-羟色胺转运体)。相比于5-羟色胺、组胺、乙酰胆碱或多巴胺受体,它对大鼠去甲肾上腺素受体的亲和力高出1,000倍以上(Ki 分别为 1.1, 129, 1,400, 3,900, 和 >10,000 nM)。
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规格 价格 库存 数量
5mg
¥245.00
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10mg
¥455.00
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25mg
¥1,085.00
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50mg
¥2,100.00
现货
100mg
¥3,360.00
现货
500mg
¥7,385.00
现货
10mM * 1mL in DMSO
¥245.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Reboxetine mesylate发表的1篇文献
  • Antonia Donat, .et al. , iScience, 2023, Aug 29;26(10):107761 PMID: 37720081
  • 生物活性
    Discription Reboxetine is an antidepressant compound that selectively inhibits norepinephrine uptake (IC50s = 8.2 and 1,070 nM for norepinephrine and serotonin transporters, respectively). It displays greater than 1,000-fold affinity for binding rat norepinephrine receptors compared to serotonin, histamine, acetylcholine, or dopamine receptors (Kis = 1.1, 129, 1,400, 3,900, and >10,000 nM, respectively).
    Targets
    Target Value
    产品信息
    目录号 A11919
    分子式 C19H23NO3.CH4SO3
    分子量 409.5
    CAS号 98769-84-7
    SMILES CCOC1=CC=CC=C1O[C@@H]([C@H]2CNCCO2)C3=CC=CC=C3.CS(=O)(=O)O
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 81 mg/mL (197.8 mM)
    Water 81 mg/mL (197.8 mM)
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.42 mL 122.1 mL 244.2 mL
    0.5 mM 4.88 mL 24.42 mL 48.84 mL
    1 mM 2.44 mL 12.21 mL 24.42 mL
    5 mM 0.49 mL 2.44 mL 4.88 mL
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