Refanezumab (GSK249320) is a humanized IgG1 monoclonal antibody targeting myelin-associated glycoprotein (MAG). This antibody specifically binds to MAG, thereby inhibiting its role in suppressing axonal regeneration. Demonstrating the ability to traverse the blood-brain barrier in animal models of stroke, Refanezumab offers promising potential for facilitating functional recovery following stroke events. This therapeutic candidate is pivotal for research focused on neural repair and neuroregenerative pathways.
Refanezumab (GSK249320) is a humanized IgG1 monoclonal antibody targeting myelin-associated glycoprotein (MAG). This antibody specifically binds to MAG, thereby inhibiting its role in suppressing axonal regeneration. Demonstrating the ability to traverse the blood-brain barrier in animal models of stroke, Refanezumab offers promising potential for facilitating functional recovery following stroke events. This therapeutic candidate is pivotal for research focused on neural repair and neuroregenerative pathways.
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