Remternetug is a human monoclonal antibody of the immunoglobulin G1-kappa class, designed to target the N3pGlu-modified peptide of amyloid beta (A??42), a key component in amyloid plaque formation associated with Alzheimer's disease. This antibody specifically recognizes the pyroglutamate form of A??, a post-translationally modified version implicated in the disease's pathology. Studies have demonstrated that Remternetug facilitates a rapid and substantial reduction in amyloid plaque deposition, making it an invaluable tool for research into the pathogenesis and potential therapeutic interventions of Alzheimer's disease.
Remternetug is a human monoclonal antibody of the immunoglobulin G1-kappa class, designed to target the N3pGlu-modified peptide of amyloid beta (A??42), a key component in amyloid plaque formation associated with Alzheimer's disease. This antibody specifically recognizes the pyroglutamate form of A??, a post-translationally modified version implicated in the disease's pathology. Studies have demonstrated that Remternetug facilitates a rapid and substantial reduction in amyloid plaque deposition, making it an invaluable tool for research into the pathogenesis and potential therapeutic interventions of Alzheimer's disease.
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