Repaglinide
目录号: A10783
Potassium Channel 抑制剂
Repaglinide 是一种强效的短效胰岛素促分泌剂,其作用机制是通过关闭胰岛β细胞质膜上的 ATP敏感性钾通道(KATP通道) 来发挥作用。
| Discription | Repaglinide is a potent short-acting insulin secretagogue that acts by closing ATP-sensitive potassium (KATP) channels in the plasma membrane of the pancreatic beta cell. | |||||
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| 目录号 | A10783 |
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| 分子式 | C27H36N2O4 |
| 分子量 | 452.59 |
| CAS号 | 135062-02-1 |
| SMILES | CCOC1=C(C=CC(=C1)CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 90 mg/mL (198.85 mM) | |
| Water | Insoluble | ||
| Ethanol | 90 mg/mL (198.85 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.1 mL | 110.48 mL | 220.95 mL |
| 0.5 mM | 4.42 mL | 22.1 mL | 44.19 mL |
| 1 mM | 2.21 mL | 11.05 mL | 22.1 mL |
| 5 mM | 0.44 mL | 2.21 mL | 4.42 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2