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Reparixin

促销

CXCL8/CXCR1/2 抑制剂

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产品目录号: A12383

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Reparixin 5mg A12383-5
¥ 1,800.00
Reparixin 10mg A12383-10
¥ 3,000.00
Reparixin 25mg A12383-25
¥ 6,800.00
Reparixin 100mg A12383-100
¥ 8,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).

Reparixin

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Reparixin 发表的文献 (1)
  • Wigenstam E, .et al. N-acetyl cysteine improves the effects of corticosteroids in a mouse model of chlorine-induced acute lung injury, Toxicology, 2015, Feb 3;328:40-7 PMID: 25497111

Chemical Information

目录号 A12383
Mechanism of action Inhibitor
分子量 283.39
化学分子式 C14H21NO3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 266359-83-5
Synonyms DF 1681Y; Repertaxin
SMILES code C[C@H](C1=CC=C(C=C1)CC(C)C)C(=O)NS(=O)(=O)C
化学名称 (R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propanamide

生物活性

Description
Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.29 mL 176.44 mL 352.87mL
0.5 mM 7.06 mL 35.29 mL 70.57 mL
1 mM 3.53 mL 17.64 mL 35.29 mL
5 mM 0.71 mL 3.53 mL 7.06 mL

*The above data is based on the productmolecular weight 283.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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