Wigenstam E, .et al. , Toxicology, 2015, Feb 3;328:40-7 PMID: 25497111
生物活性
Discription
Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
产品信息
目录号
A12383
分子式
C14H21NO3S
分子量
283.39
CAS号
266359-83-5
SMILES
C[C@H](C1=CC=C(C=C1)CC(C)C)C(=O)NS(=O)(=O)C
其他名称
DF 1681Y; Repertaxin
储存条件
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
溶解性数据
In vitro
DMSO
52 mg/mL (183.49 mM)
Water
Insoluble
Ethanol
52 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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