RepSox (SJN 2511)

Name: RepSox (SJN 2511)
SKU: A11762
Price: 175 CNY
Rating: 5 (2 reviews)

目录号: A11762

ALK5 抑制剂

2 篇发表文献

RepSox（SJN 2511）是TGF-β类型I受体ALK5的选择性抑制剂（IC50值分别为ALK5自磷酸化和ALK5结合时为0.004和0.023 μM）。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥245.00	现货
5mg	¥280.00	现货
10mg	¥385.00	现货
25mg	¥665.00	现货
50mg	¥1,085.00	现货
100mg	¥1,715.00	现货
500mg	¥4,585.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用RepSox (SJN 2511)发表的2篇文献

Wojciech J Szlachcic, .et al. , iScience, 2022, Jul 15;25(7) PMID: 35756892

Xu H, .et al. , Cancer Lett, 2020, Mar 1;472:151-164 PMID: 31846689

生物活性

Discription

RepSox (SJN 2511) is a selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11762
分子式	C17H13N5
分子量	287.32
CAS号	446859-33-2
SMILES	CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4
其他名称	E-616452, SJN 2511, ALK 5 inhibitor
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	49 mg/mL (170.54 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	34.8 mL	174.02 mL	348.04 mL
0.5 mM	6.96 mL	34.8 mL	69.61 mL
1 mM	3.48 mL	17.4 mL	34.8 mL
5 mM	0.7 mL	3.48 mL	6.96 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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