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Resminostat hydrochloride

HDAC 抑制剂

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产品目录号: A15220

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Resminostat hydrochloride 10mg A15220-10
¥ 1,700.00
Resminostat hydrochloride 50mg A15220-50
¥ 5,300.00
Resminostat hydrochloride 100mg A15220-100
¥ 8,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Resminostat hydrochloride is a potent inhibitor of HDAC1/3/6(IC50=43-72 nM); less potent to HDAC8 with IC50 of 877 nM.

Resminostat hydrochloride

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Chemical Information

目录号 A15220
Mechanism of action Inhibitor
分子量 385.87
化学分子式 C16H20ClN3O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1187075-34-8
Synonyms RAS2410 hydrochloride, 4SC-201 hydrochloride, RAS 2410 hydrochloride, RAS-2410 hydrochloride
SMILES code CN(C)CC1=CC=C(C=C1)S(=O)(=O)N2C=CC(=C2)C=CC(=O)NO.Cl
化学名称 (Z)-3-(1-((4-((dimethylamino)methyl)phenyl)sulfonyl)-1H-pyrrol-3-yl)-N-hydroxyacrylamide hydrochloride

生物活性

Description
Resminostat hydrochloride is a potent inhibitor of HDAC1/3/6(IC50=43-72 nM); less potent to HDAC8 with IC50 of 877 nM.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.92 mL 129.58 mL 259.15mL
0.5 mM 5.18 mL 25.92 mL 51.83 mL
1 mM 2.59 mL 12.96 mL 25.92 mL
5 mM 0.52 mL 2.59 mL 5.18 mL

*The above data is based on the productmolecular weight 385.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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