Resminostat

目录号: A12556

HDAC 抑制剂

Resminostat

Resminostat Chemical Structure

CAS NO. 864814-88-0

Resminostat,也称为RAS2410,是一种有效的I和II类组蛋白脱乙酰基酶(HDAC)抑制剂。它结合并抑制HDAC,从而导致高度乙酰化的组蛋白的积累。选择性的抑制HDAC1/3/6,IC50为42.5 nM/50.1 nM/71.8 nM,作用于HDAC8效果弱,IC50为877 nM。

库存: 现货

规格 价格 数量
10 mg
¥ 1,200.00
25 mg
¥ 2,500.00
50 mg
¥ 4,200.00
100 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,010.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Resminostat,也称为RAS2410,是一种有效的I和II类组蛋白脱乙酰基酶(HDAC)抑制剂。它结合并抑制HDAC,从而导致高度乙酰化的组蛋白的积累。选择性的抑制HDAC1/3/6,IC50为42.5 nM/50.1 nM/71.8 nM,作用于HDAC8效果弱,IC50为877 nM。
靶点信息
HDAC1 HDAC3 HDAC6
42.5 nM50.1 nM71.8 nM
In vitro DMSO 70 mg/mL (200.34 mM)
Water <1 mg/mL (<1 mM)
Ethanol 70 mg/mL (200.34 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.62 mL 143.1 mL 286.2 mL
0.5 mM 5.72 mL 28.62 mL 57.24 mL
1 mM 2.86 mL 14.31 mL 28.62 mL
5 mM 0.57 mL 2.86 mL 5.72 mL

*The above data is based on the productmolecular weight 349.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12556
作用机制 Inhibitor (抑制剂)
M. Wt 349.4
Formula C16H19N3O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 864814-88-0
Synonyms 4SC-201, RAS2410
SMILES CN(C)CC1=CC=C(C=C1)S(=O)(=O)N2C=CC(=C2)/C=C/C(=O)NO

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