Reversine

目录号: A13250

human A3 adenosine receptor antagonist /Aurora inhibitor

Reversine Chemical Structure

CAS NO. 656820-32-5

Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM, respectively. Also used for stem cell dedifferentiation.

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 900.00
25 mg
¥ 1,800.00
50 mg
¥ 2,500.00
10mM * 1mL in DMSO
¥ 750.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM, respectively. Also used for stem cell dedifferentiation.
Targets
Aurora A Aurora B Aurora C human A3 adenosine receptor
12 nM13 nM20 nM0.66 μM(Ki)
In vitro DMSO 82 mg/mL heating (208.52 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL heating (2.54 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.41 mL 127.06 mL 254.13 mL
0.5 mM 5.08 mL 25.41 mL 50.83 mL
1 mM 2.54 mL 12.71 mL 25.41 mL
5 mM 0.51 mL 2.54 mL 5.08 mL

*The above data is based on the productmolecular weight 393.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13250
MECHANISM OF ACTION Antagonist, Inhibitor
M. Wt 393.5
Formula C21H27N7O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 656820-32-5
Synonyms 0
SMILES C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5

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