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DNA methyltransferase 抑制剂

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产品目录号: A13054


产品名 目录号 价格 数量
RG108 25mg A13054-25
¥ 1,000.00
RG108 50mg A13054-50
¥ 1,900.00
RG108 100mg A13054-100
¥ 3,700.00
RG108 10mM * 1mL in DMSO A13054-10mM-D
¥ 600.00



RG108 is a non-nucleoside inhibitor of DNA methyltransferase with IC50 of 115 nM.





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Chemical Information

目录号 A13054
Mechanism of action Inhibitor
分子量 334.33
化学分子式 C19H14N2O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 48208-26-0
Synonyms RG 108, RG-108
SMILES code C1=CC=C2C(=C1)C(=O)N(C2=O)[C@@H](CC3=CNC4=CC=CC=C43)C(=O)O
化学名称 (S)-3-(Indol-3-yl)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propanoic acid


RG108 is a non-nucleoside inhibitor of DNA methyltransferase with IC50 of 115 nM.
DNA methyltransferase (Cell-free assay)
115 nM


Solubility (25°C)* In vitro DMSO 67 mg/mL (200.4 mM)
Water <1 mg/mL (<1 mM)
Ethanol 67 mg/mL (200.4 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.91 mL 149.55 mL 299.11mL
0.5 mM 5.98 mL 29.91 mL 59.82 mL
1 mM 2.99 mL 14.96 mL 29.91 mL
5 mM 0.6 mL 2.99 mL 5.98 mL

*The above data is based on the productmolecular weight 334.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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