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RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.91 mL | 124.55 mL | 249.1 mL |
| 0.5 mM | 4.98 mL | 24.91 mL | 49.82 mL |
| 1 mM | 2.49 mL | 12.45 mL | 24.91 mL |
| 5 mM | 0.5 mL | 2.49 mL | 4.98 mL |
*The above data is based on the productmolecular weight 401.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21816 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 401.45 |
| Formula | C22H27NO6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2072057-17-9 |
| Synonyms | RO 7020322, RO-7020322, RO7020322; RG 7834, RG-7834 |
| SMILES | O=C(O)C1=CN2[C@@H](CC3=CC(OCCCOC)=C(C=C3C2=CC1=O)OC)C(C)C |
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