产品详情
Rhosin is a potent, specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin induces cell apoptosis.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.9 mL | 139.51 mL | 279.02 mL |
0.5 mM | 5.58 mL | 27.9 mL | 55.8 mL |
1 mM | 2.79 mL | 13.95 mL | 27.9 mL |
5 mM | 0.56 mL | 2.79 mL | 5.58 mL |
*The above data is based on the productmolecular weight 358.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A21504 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 358.4 |
Formula | C20H18N6O |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1173671-63-0 |
SMILES | O=C(N/N=C/C1=CC=C2N=CC=NC2=C1)[C@H](N)CC3=CNC4=C3C=CC=C4 |
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