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RNA polymerase 抑制剂

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产品目录号: A10790


产品名 目录号 价格 数量
Rifabutin 25mg A10790-25
¥ 500.00
Rifabutin 100mg A10790-100
¥ 1,000.00
Rifabutin 200mg A10790-200
¥ 1,500.00
Rifabutin 500mg A10790-500
¥ 3,000.00
Rifabutin 10mM * 1mL in DMSO A10790-10mM-D
¥ 760.00



Rifabutin is a bactericidal antibiotic drug primarily used in the treatment of tuberculosis. Its effect is based on blocking the DNA-dependent RNA-polymerase of the bacteria.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Rifabutin 发表的文献 (2)
  • Meikle V, .et al. A protein complex from human milk enhances the activity of antibiotics and drugs against Mycobacterium tuberculosis, Antimicrob Agents Chemother, 2018, Nov 12. pii: AAC.01846-18 PMID: 30420480
  • Dinah Binte Aziz, .et al. Rifabutin Is Active against Mycobacterium abscessus Complex, Antimicrob Agents Chemother, 2017, Jun; 61(6): e00155-17 PMID: 28396540

Chemical Information

目录号 A10790
Mechanism of action Inhibitor
分子量 847.0
化学分子式 C46H62N4O11
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 72559-06-9
Synonyms Mycobutin
SMILES code C[C@H]1/C=C/C=C(\C(=O)NC2=C3C(=NC4(N3)CCN(CC4)CC(C)C)C5=C6C(=C(C(=C5C2=O)O)C)O[C@@](C6=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)/C
化学名称 N/A


Rifabutin is a bactericidal antibiotic drug primarily used in the treatment of tuberculosis. Its effect is based on blocking the DNA-dependent RNA-polymerase of the bacteria.


Solubility (25°C)* In vitro DMSO 60 mg/mL (70.83 mM)
Water <1 mg/mL (<1 mM)
Ethanol 40 mg/mL (47.22 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.81 mL 59.03 mL 118.06mL
0.5 mM 2.36 mL 11.81 mL 23.61 mL
1 mM 1.18 mL 5.9 mL 11.81 mL
5 mM 0.24 mL 1.18 mL 2.36 mL

*The above data is based on the productmolecular weight 847.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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