Rigosertib sodium

Name: Rigosertib sodium
SKU: A21824
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A21824

multi-kinase 抑制剂

Rigosertib sodium (ON-01910 sodium) 是一种多激酶抑制剂，也是一种选择性抗癌药物，它通过抑制 PI3K/Akt 通路来诱导凋亡，促进组蛋白 H2AX 的磷酸化，并在细胞周期中诱导 G2/M 阻滞。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥315.00	现货
25mg	¥560.00	现货
50mg	¥945.00	现货
100mg	¥1,610.00	现货
200mg	¥2,415.00	现货
*10mM 1mL in DMSO**	¥210.00	现货
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Data Sheet

SDS

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生物活性

Discription

Rigosertib sodium (ON-01910 sodium) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3K/Akt pathway, promotes the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A21824
分子式	C21H24NNaO8S
分子量	473.47
CAS号	592542-60-4
SMILES	COC1=CC=C(C=C1NCC([O-])=O)CS(/C=C/C2=C(C=C(C=C2OC)OC)OC)(=O)=O.[(E)].[Na+]
其他名称	ON-01910 sodium, ON01910, ON 01910
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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