Rilpivirine (R 278474, TMC 278)
目录号: A11542
NNRT 抑制剂
Rilpivirine 是一种第二代非核苷类逆转录酶抑制剂(NNRTI),与旧型 NNRTI(如 efavirenz)相比,具有更高的效力、更长的半衰期和更低的副作用。
Discription | Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. | |||||
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Cell Research |
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目录号 | A11542 |
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分子式 | C22H18N6 |
分子量 | 366.4 |
CAS号 | 500287-72-9 |
SMILES | CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N |
其他名称 | R278474, TMC278, TMC-278 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 66 mg/mL (180.12 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 27.29 mL | 136.46 mL | 272.93 mL |
0.5 mM | 5.46 mL | 27.29 mL | 54.59 mL |
1 mM | 2.73 mL | 13.65 mL | 27.29 mL |
5 mM | 0.55 mL | 2.73 mL | 5.46 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2