Rilpivirine (R 278474, TMC 278)

目录号: A11542

NNRT inhibitor

Rilpivirine (R 278474, TMC 278) Chemical Structure

CAS NO. 500287-72-9

Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.

库存: 现货

规格 价格 数量
10 mg
¥ 1,400.00
25 mg
¥ 2,400.00
50 mg
¥ 3,900.00
10mM * 1mL in DMSO
¥ 1,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
In vitro DMSO 73 mg/mL (199.22 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.29 mL 136.46 mL 272.93 mL
0.5 mM 5.46 mL 27.29 mL 54.59 mL
1 mM 2.73 mL 13.65 mL 27.29 mL
5 mM 0.55 mL 2.73 mL 5.46 mL

*The above data is based on the productmolecular weight 366.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11542
MECHANISM OF ACTION Inhibitor
M. Wt 366.4
Formula C22H18N6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 500287-72-9
Synonyms R278474, TMC278, TMC-278
SMILES CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N

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