Rimonabant (SR141716)
目录号: A11547
Rimonabant 是一种选择性的 CB1 拮抗剂,其 IC50 为 13.6 nM,EC50 为 17.3 nM,测试环境为转染了 hCB1 的 HEK 293 细胞膜。
| Discription | Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. | ||
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| Targets |
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| 目录号 | A11547 |
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| 分子式 | C22H21Cl3N4O |
| 分子量 | 463.79 |
| CAS号 | 168273-06-1 |
| SMILES | CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)Cl |
| 其他名称 | SR141716 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 22 mg/mL (47.43 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.56 mL | 107.81 mL | 215.61 mL |
| 0.5 mM | 4.31 mL | 21.56 mL | 43.12 mL |
| 1 mM | 2.16 mL | 10.78 mL | 21.56 mL |
| 5 mM | 0.43 mL | 2.16 mL | 4.31 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2