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Rimonabant (SR141716)

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产品目录号: A11547

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Rimonabant (SR141716) 10mg A11547-10
¥ 500.00
Rimonabant (SR141716) 25mg A11547-25
¥ 1,100.00
Rimonabant (SR141716) 50mg A11547-50
¥ 2,000.00
Rimonabant (SR141716) 100mg A11547-100
¥ 3,500.00
Rimonabant (SR141716) 10mM * 1mL in DMSO A11547-10mM-D
¥ 870.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane.

Rimonabant (SR141716)

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Chemical Information

目录号 A11547
Mechanism of action N/A
分子量 463.79
化学分子式 C22H21Cl3N4O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 168273-06-1
Synonyms SR141716
SMILES code CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)Cl
化学名称 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide

生物活性

Description
Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane.
Targets
hCB1 hCB2 ACAT
13.6 nM1.64 μM1.5 μM-2.9 μM

溶解性

Solubility (25°C) * In vitro DMSO 25 mg/mL (53.9 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.31 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.56 mL 107.81 mL 215.61mL
0.5 mM 4.31 mL 21.56 mL 43.12 mL
1 mM 2.16 mL 10.78 mL 21.56 mL
5 mM 0.43 mL 2.16 mL 4.31 mL

*The above data is based on the productmolecular weight 463.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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