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Riociguat (BAY 63-2521)是可溶性鸟苷酸环化酶(sGC)的刺激物。
靶点信息
| guanylate cyclase | ||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.67 mL | 118.37 mL | 236.73 mL |
| 0.5 mM | 4.73 mL | 23.67 mL | 47.35 mL |
| 1 mM | 2.37 mL | 11.84 mL | 23.67 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.73 mL |
*The above data is based on the productmolecular weight 422.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11549 |
|---|---|
| MECHANISM OF ACTION | Stimulator |
| M. Wt | 422.42 |
| Formula | C20H19FN8O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 625115-55-1 |
| Synonyms | BAY 63-2521; BAY 632521 |
| SMILES | CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC |
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